Early detection of breast cancer through mammography screening continues to save lives.

In a new Breast Cancer Surveillance Consortium (BCSC) study published in JAMA Oncology, researchers calculated the population attributable risk proportions (PARPs) for advanced breast cancer by race/ethnicity. Using the large BCSC cohort, the study evaluated 904,615 women aged 40 to 74 (with a median age of 57 years) undergoing 3,331,740 annual or biennial screening mammograms. The study found that regular screening is not always sufficient to prevent an advanced breast cancer diagnosis.

The Breast Cancer Surveillance Consortium (BCSC) has extended its version 2 invasive breast cancer risk model to include body mass index (BMI), second-degree family history of breast cancer, and age at first live birth. The new version 3 model estimates a woman’s five- and ten-year risk of developing invasive breast cancer based on her age, race and ethnicity, first- and second-degree family history, breast density, history of benign breast biopsy, BMI, and age at first live birth.

In a new Breast Cancer Surveillance Consortium (BCSC) study published in the Journal National Cancer Institute, researchers evaluated whether screening breast MRI plus mammography improves screening outcomes compared to MRI or mammography alone for women with dense versus nondense breasts. Using the large BCSC cohort, the study evaluated 52 237 women aged 40-79 years who underwent 2611 screening MRIs alone and 6518 supplemental MRI plus mammography.

UC Davis Professor and Division Chief of Biostatistics Diana Miglioretti is one of the investigators supported by NIH’s National Cancer Institute (NCI).

Children with Down syndrome often undergo extensive medical tests, including imaging, that may use ionizing radiation. At the same time, genetic disorders like Down syndrome have an established increased risk of certain cancers, making exposure to radiation early in life less than ideal. Until recently, little research had been done to measure typical imaging radiation exposure rates for children with Down syndrome.

Read full story here: https://www.bcsc-research.org/bcsc-blog/racial-ethnic-diffs-women-lump

Read full story here: https://www.bcsc-research.org/bcsc-blog/breast-dens-notif-bmi

Read full story here: https://health.ucdavis.edu/news/headlines/uc-davis-gets-15-million-to-develop-and-assess-ai-for-breast-cancer-detection-risk-model/2022/11

Read BCSC blog post here: https://www.bcsc-research.org/bcsc-blog/immed-interp-screen-mamms-reduce-harms

Read UC Davis Press release: https://health.ucdavis.edu/news/headlines/half-of-all-women-experience-false-positive-mammograms-after-10-years-of-annual-screening-/2022/03#:~:text=The%20researchers%20estimated%20that%20over,a%20false%20positive%20biopsy%20recommendation.

UC Davis Comprehensive Cancer Center will soon have new tools, including a “mammovan,” to improve breast health and early cancer detection in underserved women living in rural communities. Over a five-year period, Dr. Miglioretti and her team will develop a precision breast cancer screening research program focused on racially/ethnically diverse low-income women.

UC Davis Comprehensive Cancer Center researcher Diana Miglioretti is co-senior author of a new study that shows women 7

Senior study author Diana Miglioretti, PhD, Professor and Division Chief of Biostatistics at the University of California, Davis was featured in a February, 24th 2021 article in Health Day titled "3D Mammograms Best at Spotting Tumors, But Many Black Women Missing Out".

Diana Miglioretti, dean’s professor and division chief of biostatistics in the department of Public Health Sciences, has won the prestigious Distinguished Investigator Award from the Association of Clinical and Translational Science (ACTS).