Research Interest Areas

Dr. Miglioretti is committed to improving health care by building the evidence base for personalized breast cancer screening and by evaluating the benefits and harms of medical tests. She pursues a rigorous combination of applied and methodological research. Her work focuses on evaluating the benefits and harms of breast cancer screening, risk prediction modeling, and evaluating radiation exposure from medical imaging and associated cancer risks. 

Biostatistics

Clustered and longitudinal data analysis; latent variable modeling; assessment of diagnostic screening tests

Cancer

Biostatistics; breast cancer screening and surveillance; mammographic breast density; risk prediction modeling; lung nodule surveillance

Radiology

Radiation exposure from medical imaging; radiation-induced cancers from medical imaging; evaluation of imaging tests; trends in imaging use and associated radiation exposure; optimizing and standardizing radiation exposure from CT imaging

Screening and Surveillance

Effectiveness of different screening strategies including risk-based screening; optimizing monitoring for recurrence after breast cancer treatment

Current Studies

Dr. Miglioretti is currently a Principal Investigator or co-Principal Investigator (or other significant role) on the following studies:

• Risk-Based Breast Cancer Screening and Surveillance in Community Settings ($52M NIH/NCI P01 CA154292; Role: Contact PI)

• Precision Breast Cancer Screening for Marginalized Communities ($5M Cypress Award, Role: PI)

• Sacramento Area Breast Imaging Registry (Placer Breast Cancer Foundation, UC Davis Comprehensive Cancer Center, multiple NIH/NCI awards; Role: PI)

• Risk of Radiation-Induced Cancers from Imaging in Pediatrics and Adolescents (NIH/NCI R01 CA185687; Role: PI)

• Advancing Evidence of the Associations between specific Benign Breast Diagnoses and Future Breast Cancer Risk (NIH/NCI 1F31CA271738; Role: Primary mentor)

• UC Davis Cancer Center Support Grant (NIH/NCI P30CA093373; Role: Co-Lead of Population Sciences and Health Disparities Program)

• Watch the Spot Trial (PCORI PCS-1403-12653; Role: co-PI)

Prior Studies

• Comparative Effectiveness of Breast Cancer Screening and Diagnostic Evaluation by Extent of Breast Density (PCORI PCS-1504-30370; Role: PI)

For full list, see CV.